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Potassium Tert-Butoxide(KTB)

Potassium Tert-Butoxide(KTB)
CAS No.:865-47-4
Molecular Formula: C4H9KO
Molecular Weight: 112.213
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Product Introduction

Potassium *tert*-butoxide (CAS No. 865-47-4; molecular formula C4H9KO; molecular weight approx. 112.21) is a commonly used strong organic base reagent widely employed in pharmaceutical and chemical synthesis. According to the latest overseas research and university laboratory safety data from 2026, it exists in multiple structural forms in solution; as a corrosive solid that is flammable upon contact with water, it requires strict protective measures during handling.


CHEMICAL PROPERTIES

FormThe color of the solution may darken during storage
PSA23.06000
logP1.21540
SolubilitySoluble in hexane, toluene, diethyl ether and tetrahydrofuran.
AppearanceWhite crystalline powder
StorageStore under dry inert gas, keep the container tightly sealed, and store in a cool and dry place
Auto-ignition Temperature483°C
Chemical PropertiesWhite crystalline powder
ColorWhite to off-white
pH Value13 (5g/L, H2O, 20°C) Hydrolysis
Physical PropertiesMelting point: 256-258°C (dec.)(lit.); Boiling point: 275°C; Density: 0.910 g/mL at 20°C; Flash point: 54°F; Water solubility: REACTS
Acidity Coefficient (pKa)pK1: 18 (25°C)
SolubilitySoluble in hexane, toluene, diethyl ether and tetrahydrofuran
StabilityStable, but reacts violently with water and acids, which may cause fire. Incompatible with water, acids, halogenated hydrocarbons, alcohols, strong oxidizing agents, ketones and carbon dioxide.
Storage TemperatureFlammables area


PRODUCT USAGE

Strong base for organic synthesis: Acts as a strong basic condensing agent—with higher basicity than sodium methoxide or sodium ethoxide—and is commonly used in dehydrohalogenation reactions of halogenated hydrocarbons.

Catalysis of specific reactions: Widely used in reactions such as condensation, rearrangements (e.g., Pinacol and Favorskii rearrangements), and ring-opening; also serves as a common base for Michael addition reactions.

Industrial applications: Utilized as a key intermediate or catalyst in the production of pesticides, pharmaceuticals, dyes, catalysts, and liquid crystal materials.

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